With models like the Audi A6, BMW 5 Series, and the Jaguar XF breathing down its neck, the Mercedes-Benz E350 has stiff competition -- it's up to the challenge.

Pricing and Equipment

Mercedes-Benz E350 Side

With a base price of $53,100, the 2016 Mercedes-Benz E350 is expensive, but it features a slew of premium features that help make it easier to justify. These include:

  • 17-inch wheels
  • Leather-wrapped steering wheel
  • Power front seats
  • Eight-speaker audio system

The E350 is also available with 4MATIC all-wheel drive, and with a Sport Package that adds sport styling, a two-bar grille, a sport-tuned suspension, and 18-inch wheels at no cost.

Performance Pros

The E350 is a capable performer with with its 302-horsepower 3.5-liter V6. The engine may be getting long in the tooth, but it remains smooth and responsive throughout its powerband, the transmission shifts smoothly, and it will reach 60 mph in seven seconds flat.

Performance Cons

  • There isn't any getting around the age of that V6, though, which is due for a replacement.
  • Highway fuel economy isn't bad, but its city rating seems low to us.

Interior Pros

Mercedes-Benz E350 Interior
  • The E350's cabin is well-equipped, and there are premium features everywhere.
  • Standard MB-Tex synthetic upholstery is a great alternative to leather.
  • Fit and finish is also spot on, and matches up well with the exterior look of the E-Class.
  • Good rear legroom.

Interior Cons

We can find a few flaws with the cabin of the E350:

  • Material used for the buttons could use some improvement.
  • The Comand interface can be pretty overwhelming to use.

The Most Pleasant Surprise

Many cars that we test do not have much cohesiveness between their exteriors and interiors. The E350, however, aces this, as the shape and style inside the cabin align perfectly with the body. Both boast designs that are stylish yet reserved, a pretty tough combination to pull off.

The Least Pleasant Surprise

We understand that these systems get easier the longer you own a car, but the Comand system has a pretty steep learning curve.

The Bottom Line

Mercedes-Benz E350 Red

The E350 has long been the go-to model for midsize luxury car shoppers, and the 2016 model continues this domination in its class. It delivers style and class in a package that can haul around most small families in comfort.